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Gemcitabine plus vinorelbine chemotherapy in locally advanced and/or metastatic breast cancer. The aim of this study was to evaluate the activity and safety of gemcitabine plus vinorelbine as first-line chemotherapy in patients with locally advanced and/or metastatic breast cancer. The primary end-point was overall response rate (ORR). The secondary end-points were time to progression (TTP), clinical benefit rate (CBR), and safety. Forty patients were enrolled in the study. Eleven out of 40 (27.5%) had a partial response and 21 out of 40 (52.5%) had stable disease. The median duration of response was 6 months. The median TTP was 7 months and median overall survival time was 15 months. The most common grade 3/4 toxicities were neutropenia (40%), leukopenia (15%), and thrombocytopenia (5%). The combination of gemcitabine plus vinorelbine is a feasible and well-tolerated regimen with an acceptable safety profile and encouraging activity.Parents of children with autism often feel that the social behavior of their kids is more problematic than their social skills. What they often overlook is the fact that children with autism are not lacking in social skills — it’s just that the rules of social interaction are not obvious to them. When the Parents of Socially Awkward Kids Are Incorrect, They Will Likely Take It Out on the Kids If you are a parent of a child with autism, you may have felt frustrated by the fact that, with your best intentions, your child’s behavior makes it difficult to interact socially. You may have experienced feelings such as anger, anxiety, frustration, or even a sense of resentment. As much as you may want to do the right thing in your interactions with your child, your reactions to the socially awkward behavior may cause you to lash out or get frustrated. A study by Thomas Bopp and colleagues at Yale University shows that parents of socially awkward children lash out at their children with more intensity when they are experiencing negative emotions. Let’s take a look at how your feelings may influence the ways you react to your child with autism. Your Parents’ Behavior May Influence How You React to Your Child with Autism Sometimes, you are right to get frustrated by the socially awkward behavior of your child. One study by Alexandra King and

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Download Cs Bte 2.5 Full |VERIFIED| 11

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